Intra-uterine insemination (IUI) is a procedure where husband's semen is collected first. That semen sample has to be processed because raw semen has prostaglandins and they can cause severe uterine cramping and contractions and thus cannot be used for IUI. By washing the semen sample, seminal plasma and prostaglandins are removed and sperm can then be used for IUI.
Washed sperm is placed inside an insemination catheter and that catheter then passes through cervix and enters into uterine cavity and sperm is deposited inside the uterine cavity.
IUI is indicated for :
IUI can be used in males with retrograde ejaculation, hypospadias, or someone with reduced sperm quality. In females, IUI can be used in someone with cervical factor infertility, such as patients with chronic cervicitis, severely anteverted uterus, or retroverted uterus, or patients with poor cervical mucus or someone with cervical cone biopsy. All these cervical problems will prevent sperm entry into the uterus. IUI can help sperm bypass the cervical obstruction and enter the uterine cavity and then migrate to the fallopian tubes. IUI can also be used in couples with unexplained infertility.